SHAPIRO B. Jesse

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  • Microbial Evolutionary Genomics, UniversitĂ© de MontrĂ©al, Montreal, Canada
  • Evolutionary genomics, Metagenomics, Population genomics, Bioinformatics
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1 recommendation

2020-09-24
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A rapid and simple method for assessing and representing genome sequence relatedness
M Briand, M Bouzid, G Hunault, M Legeay, M Fischer-Le Saux, M Barret
10.1101/569640

Recommended by B. Jesse Shapiro based on reviews by Gavin Douglas and 1 anonymous reviewer
A quick alternative method for resolving bacterial taxonomy using short identical DNA sequences in genomes or metagenomes

The bacterial species problem can be summarized as follows: bacteria recombine too little, and yet too much (Shapiro 2019).
Too little in the sense that recombination is not obligately coupled with reproduction, as in sexual eukaryotes. So the Biological Species Concept (BSC) of reproductive isolation does not strictly apply to clonally reproducing organisms like bacteria. Too much in the sense that genetic exchange can occur promiscuously across species (or even Domains), potentially obscur...

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